Engineering
Chemistry
Preparation of Amines
Test of amines
Question
Illustrate the following reactions by giving chemical equations in each case:
  • Gabriel phthalimide synthesis
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Solution
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Gabriel phthalimide synthesis is used for the preparation of aliphatic primary amines.In this reaction, phthalimide is first of all treated with ethanolic KOH to form potassium phthalimide. Potassium phthalimide on treatment with alkyl halide gives N-alkyl phthalimide, which on hydrolysis with dilute hydrochloric acid gives a primary amine as the product.

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