A simple mechanism for enzyme-catalyzed reaction is given by the following set of equations
E + S ⇌ ES
(enzyme) (reactant) (intermediate-1)
ES ⇌ EP
(intermediate-1) (intermediate-2)
EP ⇌ E + P
(intermediate-2) (enzyme) (product)
This is known as the Michaelis–Menten mechanism. The potential energy diagram is shown in the fig. Which of the following sets of identifications is correct ? (Assume that the temperature and pressure are constant).
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Intermediate and product have less potential energy than activated complex.